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CNTA vs SPY

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Centessa Pharmaceuticals plc (CNTA) vs State Street SPDR S&P 500 ETF Trust (SPY) total return over 5Y: CNTA +151.40%, SPY +91.36%. Regime CNTA BULL · SPY BULL. As of Oct 9, 2026. Research only.

CNTACentessa Pharmaceuticals plcSPYState Street SPDR S&P 500 ETF Trust
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Total return · dividends and splits
-78%-39%0%+39%+78%+117%10-13’2108-11’2206-09’2304-09’2402-06’2512-0410-05’26CNTA +151.4%SPY +91.4%lopjlb.com
CNTA
SPY
SYMBOLPRICECHANGE5Y %PREV CLOSEDIRREGIME
CNTACentessa Pharmaceuticals plc$40.50—+0.00%+151.40%—🔒🔒
SPYState Street SPDR S&P 500 ETF Trust$778.57—+0.60%+91.36%—🔒🔒
DRAWDOWN · THIS RANGE
SYMBOLCURRENTPEAKWORSTTROUGH
CNTA+0.00%2026-06-23-82.73%2023-02-16
SPY-0.07%2026-10-06-24.49%2022-10-12
PERIODS · 5Y BOOK
SYMBOL1Y2Y3Y5Y
CNTA----
SPY----
ANNUAL · 5Y BOOK
YEARCNTASPY
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Compare FAQ

What does the CNTA vs SPY overlay show?
LOPJLB overlays CNTA vs SPY as total return (dividends and splits) from the first adjusted close in the selected 5Y window. Each path starts at 0% so you can read relative holding performance, not raw tape price.
Is this holding return or tape close?
Holding return. The series uses split- and dividend-adjusted close (Yahoo-style backward adjustment) when dividend coverage is sufficient, otherwise it falls back to tape close. Candles and technical overlays on /chart stay tape.
Which windows are public?
Public visitors can share 1M, 3M, 6M, YTD, 1Y, and 5Y. MAX is Research+. Direction and regime in the table follow the desk ladder: SPY25 on Free, full book on Essential+.
How do I read the drawdown, period, and annual tables?
Drawdowns are current and worst peak-to-trough on the visible range. Periods are calendar lookbacks (1Y / 2Y / 3Y / 5Y, plus 10Y on MAX) from the last bar. Annual is calendar-year holding return, with the latest year labeled YTD.
How has CNTA vs SPY performed on a normalized basis?
CNTA vs SPY holding-return overlay: 5Y CNTA +151.40% · SPY +91.36%; worst drawdown CNTA -82.73% · SPY -24.49%; YTD CNTA +70.96% · SPY +14.86%. Numbers update from the live compare-series book.
Is ticker compare investment advice?
No. The overlay is research context only — not a recommendation to buy or sell any security.

Related: CNTA, SPY, methodology, chart

Centessa Pharmaceuticals plc (CNTA) vs State Street SPDR S&P 500 ETF Trust (SPY) Stock Comparison | LOPJLB