# Nuwellis, Inc. (NUWE) vs State Street SPDR S&P 500 ETF Trust (SPY) · total-return overlay

LOPJLB holding-return compare (5Y). Dividends and splits. Each path starts at 0% from the first adjusted close in the window.

Nuwellis, Inc. (NUWE) vs State Street SPDR S&P 500 ETF Trust (SPY) total return over 5Y: NUWE -100.00%, SPY +91.57%. Regime NUWE CRISIS · SPY BULL. As of Oct 9, 2026. Research only.

- Interactive: https://www.lopjlb.com/vs/NUWE/SPY
- API: `GET /bff/api/bigfive/compare-series?symbols=NUWE%2CSPY&range=5y`

## Window

| Symbol | Window % | Worst drawdown | YTD |
|---|---:|---:|---:|
| NUWE | -100.00% | -100.00% | -98.91% |
| SPY | +91.57% | -24.49% | +14.86% |

## Periods (calendar lookback)

| Symbol | 1Y | 2Y | 3Y | 5Y |
|---|---:|---:|---:|---:|
| NUWE | -99.45% | -99.97% | -100.00% | -100.00% |
| SPY | +17.26% | +38.01% | +86.77% | +91.57% |

## Annual

| Year | NUWE | SPY |
|---|---:|---:|
| YTD | -98.91% | +14.86% |
| 2025 | -96.55% | +18.01% |
| 2024 | -95.40% | +25.59% |
| 2023 | -94.51% | +26.73% |
| 2022 | -91.35% | -18.64% |
| 2021 | -45.71% | +9.65% |

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Research context only. Not personalized investment advice.