# Nkarta, Inc. (NKTX) vs State Street SPDR S&P 500 ETF Trust (SPY) · total-return overlay

LOPJLB holding-return compare (5Y). Dividends and splits. Each path starts at 0% from the first adjusted close in the window.

Nkarta, Inc. (NKTX) vs State Street SPDR S&P 500 ETF Trust (SPY) total return over 5Y: NKTX -88.93%, SPY +84.62%. Regime NKTX CRISIS · SPY BULL. As of Oct 14, 2026. Research only.

- Interactive: https://www.lopjlb.com/vs/NKTX/SPY
- API: `GET /bff/api/bigfive/compare-series?symbols=NKTX%2CSPY&range=5y`

## Window

| Symbol | Window % | Worst drawdown | YTD |
|---|---:|---:|---:|
| NKTX | -88.93% | -93.30% | +8.56% |
| SPY | +84.62% | -24.49% | +13.53% |

## Periods (calendar lookback)

| Symbol | 1Y | 2Y | 3Y | 5Y |
|---|---:|---:|---:|---:|
| NKTX | -15.06% | -48.48% | +37.16% | -88.93% |
| SPY | +17.47% | +34.75% | +83.03% | +84.62% |

## Annual

| Year | NKTX | SPY |
|---|---:|---:|
| YTD | +8.56% | +13.53% |
| 2025 | -26.00% | +18.01% |
| 2024 | -60.91% | +25.59% |
| 2023 | +9.45% | +26.73% |
| 2022 | -60.04% | -18.64% |
| 2021 | -16.30% | +6.90% |

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Research context only. Not personalized investment advice.