# Nephros, Inc. (NEPH) vs State Street SPDR S&P 500 ETF Trust (SPY) · total-return overlay

LOPJLB holding-return compare (5Y). Dividends and splits. Each path starts at 0% from the first adjusted close in the window.

Nephros, Inc. (NEPH) vs State Street SPDR S&P 500 ETF Trust (SPY) total return over 5Y: NEPH -59.48%, SPY +90.43%. Regime NEPH CRISIS · SPY BULL. As of Oct 8, 2026. Research only.

- Interactive: https://www.lopjlb.com/vs/NEPH/SPY
- API: `GET /bff/api/bigfive/compare-series?symbols=NEPH%2CSPY&range=5y`

## Window

| Symbol | Window % | Worst drawdown | YTD |
|---|---:|---:|---:|
| NEPH | -59.48% | -88.79% | -30.74% |
| SPY | +90.43% | -24.49% | +14.17% |

## Periods (calendar lookback)

| Symbol | 1Y | 2Y | 3Y | 5Y |
|---|---:|---:|---:|---:|
| NEPH | -36.24% | +119.33% | +98.19% | -59.48% |
| SPY | +16.22% | +38.14% | +85.65% | +90.43% |

## Annual

| Year | NEPH | SPY |
|---|---:|---:|
| YTD | -30.74% | +14.17% |
| 2025 | +234.25% | +18.01% |
| 2024 | -57.14% | +25.59% |
| 2023 | +211.71% | +26.73% |
| 2022 | -81.05% | -18.64% |
| 2021 | -27.34% | +9.65% |

---

Research context only. Not personalized investment advice.