# Interpace Biosciences, Inc. (IDXG) vs State Street SPDR S&P 500 ETF Trust (SPY) · total-return overlay

LOPJLB holding-return compare (5Y). Dividends and splits. Each path starts at 0% from the first adjusted close in the window.

Interpace Biosciences, Inc. (IDXG) vs State Street SPDR S&P 500 ETF Trust (SPY) total return over 5Y: IDXG -87.43%, SPY +80.34%. As of Oct 26, 2026. Research only.

- Interactive: https://www.lopjlb.com/vs/IDXG/SPY
- API: `GET /bff/api/bigfive/compare-series?symbols=IDXG%2CSPY&range=5y`

## Window

| Symbol | Window % | Worst drawdown | YTD |
|---|---:|---:|---:|
| IDXG | -87.43% | -93.11% | -7.56% |
| SPY | +80.34% | -24.49% | +12.91% |

## Periods (calendar lookback)

| Symbol | 1Y | 2Y | 3Y | 5Y |
|---|---:|---:|---:|---:|
| IDXG | +0.00% | -59.41% | +30.95% | -87.43% |
| SPY | +12.90% | +34.81% | +92.39% | +80.34% |

## Annual

| Year | IDXG | SPY |
|---|---:|---:|
| YTD | -7.56% | +12.91% |
| 2025 | -53.58% | +18.01% |
| 2024 | +145.45% | +25.59% |
| 2023 | +6.93% | +26.73% |
| 2022 | -85.87% | -18.64% |
| 2021 | -14.63% | +5.00% |

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Research context only. Not personalized investment advice.