# Carisma Therapeutics, Inc. (CARM) vs State Street SPDR S&P 500 ETF Trust (SPY) · total-return overlay

LOPJLB holding-return compare (5Y). Dividends and splits. Each path starts at 0% from the first adjusted close in the window.

Carisma Therapeutics, Inc. (CARM) vs State Street SPDR S&P 500 ETF Trust (SPY) total return over 5Y: CARM -100.00%, SPY +90.43%. Regime CARM CRISIS · SPY BULL. As of Oct 8, 2026. Research only.

- Interactive: https://www.lopjlb.com/vs/CARM/SPY
- API: `GET /bff/api/bigfive/compare-series?symbols=CARM%2CSPY&range=5y`

## Window

| Symbol | Window % | Worst drawdown | YTD |
|---|---:|---:|---:|
| CARM | -100.00% | -100.00% | -98.86% |
| SPY | +90.43% | -24.49% | +14.17% |

## Periods (calendar lookback)

| Symbol | 1Y | 2Y | 3Y | 5Y |
|---|---:|---:|---:|---:|
| CARM | -99.81% | -99.94% | -99.99% | -100.00% |
| SPY | +16.22% | +38.14% | +85.65% | +90.43% |

## Annual

| Year | CARM | SPY |
|---|---:|---:|
| YTD | -98.86% | +14.17% |
| 2025 | -90.23% | +18.01% |
| 2024 | -85.25% | +25.59% |
| 2023 | -98.73% | +26.73% |
| 2022 | -28.75% | -18.64% |
| 2021 | +10.11% | +9.65% |

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Research context only. Not personalized investment advice.