# Azora Therapeutics, Inc. (AZR) vs State Street SPDR S&P 500 ETF Trust (SPY) · total-return overlay

LOPJLB holding-return compare (5Y). Dividends and splits. Each path starts at 0% from the first adjusted close in the window.

Azora Therapeutics, Inc. (AZR) vs State Street SPDR S&P 500 ETF Trust (SPY) total return over 5Y: AZR -99.75%, SPY +78.88%. As of Oct 29, 2026. Research only.

- Interactive: https://www.lopjlb.com/vs/AZR/SPY
- API: `GET /bff/api/bigfive/compare-series?symbols=AZR%2CSPY&range=5y`

## Window

| Symbol | Window % | Worst drawdown | YTD |
|---|---:|---:|---:|
| AZR | -99.75% | -99.94% | -18.67% |
| SPY | +78.88% | -24.49% | +13.50% |

## Periods (calendar lookback)

| Symbol | 1Y | 2Y | 3Y | 5Y |
|---|---:|---:|---:|---:|
| AZR | -44.23% | -80.86% | -89.99% | -99.75% |
| SPY | +13.13% | +35.30% | +91.97% | +78.88% |

## Annual

| Year | AZR | SPY |
|---|---:|---:|
| YTD | -18.67% | +13.50% |
| 2025 | -79.25% | +18.01% |
| 2024 | -42.29% | +25.59% |
| 2023 | -69.00% | +26.73% |
| 2022 | -92.03% | -18.64% |
| 2021 | -14.01% | +3.61% |

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Research context only. Not personalized investment advice.