# Artelo Biosciences, Inc. (ARTL) vs State Street SPDR S&P 500 ETF Trust (SPY) · total-return overlay

LOPJLB holding-return compare (5Y). Dividends and splits. Each path starts at 0% from the first adjusted close in the window.

Artelo Biosciences, Inc. (ARTL) vs State Street SPDR S&P 500 ETF Trust (SPY) total return over 5Y: ARTL -99.44%, SPY +90.43%. Regime ARTL CRISIS · SPY BULL. As of Oct 8, 2026. Research only.

- Interactive: https://www.lopjlb.com/vs/ARTL/SPY
- API: `GET /bff/api/bigfive/compare-series?symbols=ARTL%2CSPY&range=5y`

## Window

| Symbol | Window % | Worst drawdown | YTD |
|---|---:|---:|---:|
| ARTL | -99.44% | -99.64% | -70.52% |
| SPY | +90.43% | -24.49% | +14.17% |

## Periods (calendar lookback)

| Symbol | 1Y | 2Y | 3Y | 5Y |
|---|---:|---:|---:|---:|
| ARTL | -91.96% | -94.43% | -95.48% | -99.44% |
| SPY | +16.22% | +38.14% | +85.65% | +90.43% |

## Annual

| Year | ARTL | SPY |
|---|---:|---:|
| YTD | -70.52% | +14.17% |
| 2025 | -81.35% | +18.01% |
| 2024 | -23.19% | +25.59% |
| 2023 | -52.86% | +26.73% |
| 2022 | -66.16% | -18.64% |
| 2021 | -29.57% | +9.65% |

---

Research context only. Not personalized investment advice.