# Amarin Corporation plc (AMRN) vs State Street SPDR S&P 500 ETF Trust (SPY) · total-return overlay

LOPJLB holding-return compare (5Y). Dividends and splits. Each path starts at 0% from the first adjusted close in the window.

Amarin Corporation plc (AMRN) vs State Street SPDR S&P 500 ETF Trust (SPY) total return over 5Y: AMRN -88.85%, SPY +88.08%. Regime AMRN CRISIS · SPY BULL. As of Oct 12, 2026. Research only.

- Interactive: https://www.lopjlb.com/vs/AMRN/SPY
- API: `GET /bff/api/bigfive/compare-series?symbols=AMRN%2CSPY&range=5y`

## Window

| Symbol | Window % | Worst drawdown | YTD |
|---|---:|---:|---:|
| AMRN | -88.85% | -92.26% | -15.96% |
| SPY | +88.08% | -24.49% | +14.79% |

## Periods (calendar lookback)

| Symbol | 1Y | 2Y | 3Y | 5Y |
|---|---:|---:|---:|---:|
| AMRN | -39.85% | -0.95% | -19.43% | -88.85% |
| SPY | +18.62% | +36.24% | +86.06% | +88.08% |

## Annual

| Year | AMRN | SPY |
|---|---:|---:|
| YTD | -15.96% | +14.79% |
| 2025 | +33.33% | +18.01% |
| 2024 | -45.44% | +25.59% |
| 2023 | -26.89% | +26.73% |
| 2022 | -65.53% | -18.64% |
| 2021 | -34.82% | +7.72% |

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Research context only. Not personalized investment advice.